We can know God.

[The Bible] insists on beginning with a Creator whose being is utterly different from the being of creation. Second, it argues that because of this he can be known by his creatures. While, of course, we can never know God exhaustively, yet we may know him truly, in his essence. Even unbelievers know God, though they try to suppress the knowledge of him (Rom 1:18-21). Paul reminds his Roman readers that they ought never say, "who will ascend to heaven?" (to bring Christ down) or "Who will descend into the abyss?" (to bring Christ up from the dead), because he is as near to us as the word of faith (Rom. 10:6-11). The essence of God is that he is both free and owerful. In freedom, not obligation, and usinghis great power, he chose to make the world. He has structured it so that everyone made as God's image can know him, in his essence. Similarly, he decided to redeem the world, through his dying, risen Son. He structured redemption so that his people may know their God, in his essence as Savior.

From Modern Reformation Magazine, March/April 2006: "Proving God's Existence: Beside the Point?" (pgs 8-10)